Growth hormone

GHRP-6

Name: GHRP-6: uses, evidence and safety
Creator: Cited Peptides Editorial

Raising growth hormone; known for increasing appetite.

By Cited Peptides Editorial Updated 2026-10-10 Medical review pending

This page has not yet been reviewed by a credentialed medical professional. It is educational and is not medical advice.

GHRP-6: key facts

Evidence level Human trials
Approved as a medicineNo
Randomized trials on PubMed19
Papers on PubMed638
Trials testing it (ClinicalTrials.gov)None found
In tested sportProhibited

In one sentence: GHRP-6 is not an approved medicine. Its strongest evidence is human trials, with 19 randomized trials on PubMed that mention it.

What the evidence says

Studied in small human physiology trials; no approved use.

Key studies

Randomized trials Listed on PubMed as randomized trials that mention it. Some only measure it rather than test it as a treatment.

Clinical Trial, Randomized Controlled Trial1995 Growth hormone secretion after the administration of GHRP-6 or GHRH combined with GHRP-6 does not decline in late adulthood Clin Endocrinol (Oxf) PMID 7734029 → Clinical Trial, Randomized Controlled Trial2003 GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing's disease: comparison with DDAVP J Endocrinol Invest PMID 12809173 → Randomized Controlled Trial, Research Support, Non-U.S. Gov't2007 Decreased ghrelin-induced GH release in thyrotoxicosis: comparison with GH-releasing peptide-6 (GHRP-6) and GHRH Pituitary PMID 17410412 → Clinical Trial, Randomized Controlled Trial1995 The effect of an opiate antagonist on the hormonal changes induced by hexarelin Clin Endocrinol (Oxf) PMID 7586608 → Clinical Trial, Randomized Controlled Trial1999 Acute dexamethasone administration enhances GH responsiveness to GH releasing peptide-6 (GHRP-6) in man Clin Endocrinol (Oxf) PMID 10583306 →

Reviews Summaries of other studies.

Research Support, Non-U.S. Gov't, Review1997 Growth hormone-releasing peptides Eur J Endocrinol PMID 9186261 → Review2008 Diagnosis of adult GH deficiency Pituitary PMID 18404387 → Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.2005 Physiology of ghrelin and related peptides Domest Anim Endocrinol PMID 15927771 → Review2001 Growth hormone secretagogue receptor family members and ligands Endocrine PMID 11322507 →

Other notable papers The most relevant other papers on PubMed.

Review2007 Growth hormone levels in the diagnosis of growth hormone deficiency in adulthood Pituitary PMID 17429591 → Review2011 Water-in-oil microemulsions for effective transdermal delivery of proteins Expert Opin Drug Deliv PMID 21413905 → Review2020 Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36) Biomedicines PMID 32717955 → Research Support, Non-U.S. Gov't, Review2000 Growth hormone-releasing peptides and the cardiovascular system Ann Endocrinol (Paris) PMID 10790589 →

See its full evidence profile and newest papers →

Clinical trials

No registered trials list GHRP-6 as a treatment.

That usually means it hasn't been properly tested in people.

Search all trials live →

Where it fits

GoalPeptides for muscle & growth hormone ComparisonCJC-1295 vs GHRP-6 ComparisonIpamorelin vs GHRP-6 ComparisonTesamorelin vs GHRP-6 ComparisonSermorelin vs GHRP-6

Common questions

Is GHRP-6 approved?

No. GHRP-6 is not an approved medicine in the US or Canada.

Has GHRP-6 been tested in people?

19 randomized trials on PubMed mention it. Studied in small human physiology trials; no approved use.

Is GHRP-6 allowed in sport?

No. It is prohibited by the World Anti-Doping Agency.

This is a short, data-driven profile. Study and trial lists come from PubMed and ClinicalTrials.gov and are refreshed periodically. "What people use it for" describes common claims, not recommendations. Educational only, not medical advice.